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Carbenicillin disodium salt

BioChemika, ≥90% (anhydrous basis)

Synonym:α-Carboxybenzylpenicillin disodium salt
CAS Number:4800-94-6
Linear Formula:C17H16N2Na2O6S
Molecular Weight:422.36
Beilstein Registry Number:5722128
EC Number:225-360-8
MDL number:MFCD00077683

Description

Analysis NoteStable at 37 °C for 3 days
Biochem/physiol ActionsCarboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin.
Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.
Other NotesParenteral antibiotic active against Pseudomonas aeruginosa.; Characterization of two chromosome-encoded β-lactamases from Citrobacter diversus ULA-271

Properties

product lineBioChemika
assay≥90% (anhydrous basis)
solubilityH2O: 50 mg/mL
storage temp.2-8°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard CodesXn
Risk Statements42/43
Safety Statements22-36/37
WGK Germany2
RTECSON9105000

Related Products

Replaced byC3416, Carbenicillin disodium salt

References

Cited Reference1. G. Amicosante et al. Biochem. J. 254, 885, (1988) Abstract
referenceMandell, G., Antibacterial agents: Penicillins, cephalosporins, and other β-lactam antibiotics. Goodman and Gilman’s The Pharmacological Basis of Therapeutics 9th ed., New York, NY , (1996), 1074
 Raleigh, E.A. , Escherichia coli, plasmids and bacteriophages. Short Protocols in Molecular Biology 2nd ed., New York, NY , (1992), 1
 Perlman, D, Use of antibiotics in cell culture media. Meth. Enzymol. New York, NY LVIII, 112, (1979)
MerckMerck 13,1801